Description
Product Characteristics: This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH -dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants.,KCNK9,K2p9.1,KT3.2,TASK-3,TASK3,Cancer,Neuroscience,KCNK9
Target Information: This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains, and is highly expressed in the cerebellum. Amplification and overexpression of this gene has been observed in several types of human carcinomas, notably in breast cancer. This gene is imprinted in fetal brain, with preferential expression from the maternal allele. [provided by RefSeq, Oct 2010]